http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0381694-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_782b276beee7c34efe50183392517dfb |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2015-0222 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2015-0038 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2015-1075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N15-1459 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6402 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N15-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N15-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 |
filingDate | 1988-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ca36055adf6d09666961ab27a8bf295 |
publicationDate | 1990-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0381694-A1 |
titleOfInvention | DETECTING SINGLE MOLECULES. |
abstract | The detection system described by the present invention makes it possible to identify individual particles or molecules having a characteristic emission in a flow train of particles in a flow cell (22). A position sensitive detector (26) is placed adjacent to the flow cell (22) in an effective position to detect emissions from the particles in the flow cell (22) and to assign coordinates over time and in space for detected emissions. A computer (36) is then validated to predict the coordinates in space and time for the particle in the flow train based on a first detected emission. Comparison equipment or software then compares the later coordinates detected in space and time to the predicted coordinates in space and time to determine whether emissions detected later come from a particle in the train. particles. In one embodiment, the particles include fluorescent dyes which are excited to be fluorescent in a spectrum characteristic of the particle in question. Photons are emitted adjacent at least to a microchannel plate detector (26) to validate the coordinates in space and time to be affected. The purpose of comparing detected coordinates to predicted coordinates is to define a moving sample volume that effectively prevents the effects of background emissions. |
priorityDate | 1987-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Predicate | Subject |
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isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID235227 http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID453524733 |
Total number of triples: 20.