http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0381694-A1

Outgoing Links

Predicate Object
assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_782b276beee7c34efe50183392517dfb
classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2015-0222
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2015-0038
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2015-1075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N15-1459
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6402
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428
classificationIPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N15-02
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N15-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64
filingDate 1988-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ca36055adf6d09666961ab27a8bf295
publicationDate 1990-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0381694-A1
titleOfInvention DETECTING SINGLE MOLECULES.
abstract The detection system described by the present invention makes it possible to identify individual particles or molecules having a characteristic emission in a flow train of particles in a flow cell (22). A position sensitive detector (26) is placed adjacent to the flow cell (22) in an effective position to detect emissions from the particles in the flow cell (22) and to assign coordinates over time and in space for detected emissions. A computer (36) is then validated to predict the coordinates in space and time for the particle in the flow train based on a first detected emission. Comparison equipment or software then compares the later coordinates detected in space and time to the predicted coordinates in space and time to determine whether emissions detected later come from a particle in the train. particles. In one embodiment, the particles include fluorescent dyes which are excited to be fluorescent in a spectrum characteristic of the particle in question. Photons are emitted adjacent at least to a microchannel plate detector (26) to validate the coordinates in space and time to be affected. The purpose of comparing detected coordinates to predicted coordinates is to define a moving sample volume that effectively prevents the effects of background emissions.
priorityDate 1987-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

Predicate Subject
isDiscussedBy http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID235227
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID453524733

Total number of triples: 20.