abstract |
isoprenoid derivatives represented by general formula (I), wherein R represents a hydrogen atom or a lower alkyl group, X represents -CH 2 -, -0- or -NH-, n represents 1 or 2, the number of double bonds of trans configuration, and m represents an integer of 0 to 3. The compounds have the activity of inhibiting the action of 5-lipoxygenase and are useful as drugs for treating allergy, nephritis, hepatitis, rheumatism, gastric ulcer, etc. |