abstract |
The invention describes a process for the synthesis of a compound of formula: in which - X = O or NR, - Z = electro-attractor group, - R = H, CN, NO₂, - R₁ + R₂ + NC = X = 5 or 6-membered heterocycle, - R₃ = H, R₄ = OH or R₃ + R₄ = bond, process in which intermediate compounds of formula: in which R₅ = H, Br or N (R₁) CXR₂ intervene.n n n This synthesis process does not involve an epoxide derivative of chroman.n n n The new compounds of formula (IX) constitute another object of the invention. |