| abstract |
The invention relates to new phenylethanolamines of the general formula in the A is a straight-chain or branched alkylene group, B is a bond, an alkylene group, a carbonyl or hydroxymethylene group, R₁ represents a hydrogen atom, a halogen atom or a trifluoromethyl group, R₂ is a hydrogen atom or an amino group, R₃ is a cyano group, a hydrogen, chlorine or bromine atom and R₄ represents a hydrogen or halogen atom, an alkyl, hydroxy, alkoxy, carboxy, alkoxycarbonyl, aminocarbonyl, alkylaminocarbonyl or dialkylaminocarbonyl group or an alkoxy group which is terminated by a carboxy, alkoxycarbonyl, aminocarbonyl, alkylaminocarbonyl, Dialkylaminocarbonyl, hydroxy, alkoxy, amino, alkylamino, dialkylamino, pyrrolidino, piperidino or hexamethyleneimino group is substituted, mean their optical isomers and their diastereomers and their acid addition salts. n n n The new compounds of the formula I, their optical isomers and their diastereomers and their acid addition salts, in particular their physiologically tolerable acid addition salts with inorganic or organic acids, have valuable pharmacological properties, namely an action on the metabolism, preferably an antihypertensive and body fat reducing effect these are used as performance enhancers in animals.n n n The new compounds of the general formula I above can be prepared by processes which are known per se. |