| abstract |
Compounds of structure (I)n in which the dotted lines indicate the optional presence of a double bond, X¹, X² and X³ are H, halogen, CF₃, C₁₋₆alkyl, C₁₋₆alkoxy, CN, NO₂, N(R¹)₂, CHO or CO₂R¹; R¹ is H or C₁₋₈alkyl and R is hydrogen, hydroxy or acetoxy; processes for their preparation, compositions containing them and their use in medicine as inhibitors of 5-α-reductase. |