http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0375058-A3

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filingDate 1989-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1991-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0375058-A3
titleOfInvention New retro-inverso analogues of trymopentin, the method for their synthesis and their use in the preparation of pharmaceutical compositions
abstract New analogues of thymopentin (TP5) and of its tetrapeptide fragment (TP5<1><-><4>) containing two non-contiguous retro-inverted bonds in the peptide chain are described. The new compounds, of general formula (I) <CHEM> where R is hydrogen or an acyl radical, and R<1> is an -OR<2> group or an <CHEM> group where R<2> is a hydrogen atom or a hydrocarbon radical, and R<3> is a hydrogen atom or a hydroxyl group, and the corresponding pharmaceutically acceptable salts of acid or basic addition, possess immunomodulating activity.
priorityDate 1988-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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