| abstract |
In accordance with the present invention, disclosed herein are compounds of the formulan wherein R is hydrogen, straight or branched loweralkyl, cycloalkyl, amino, loweralkoxy or acylamino, and R₁ is straight or branched loweralkyl, amino, cyclohexyl, morpholino, piperidino, tetrahydrofuranyl, dihydrofuranyl, furanyl, tetrahydropyranyl, dioxolanyl, 2,2-dimethyl dioxolanyl, dioxanyl, pyrrolidinyl, tetrahydrooxazolyl, and dihydrooxazolyl, R₂ is hydrogen or -COR₃ wherein R₃ is straight or branched loweralkyl, provided, however, when R₁ is loweralkyl or cyclohexyl, R₂ is not hydrogen, and pharmaceutically acceptable salts thereof. The compounds are useful in the treatment of glaucoma. |