| abstract |
The invention provides the use of a compound of the formula:n R is hydrogen, hydroxy, aliphatic(C₁₋₂₀), (CH₂) n -Q, where n is 0-20 and Q is phenyl, thienyl, furyl, pyridyl, or (CH₂) n -T where n is 0-20 and T is an aliphatic ring of 3 to 7 carbon atoms, or =0 or a ketal of 2-5 carbons, or hydroxy, or O-aliphatic (C₁₋₁₀),or N(R₁)₂ where R₁ is hydrogen or alkyl of 1 to 5 carbons, or thiazolidine, or a sugar; and Z is -OH or a pharmaceutically acceptable salt thereof, OR₃ where R₃ is an aliphatic group of 1-10 carbons, N(R₁)₂ when R₁ is hydrogen or alkyl of 1-5 carbon atoms, in the preparation of a medicament for delaying the onset of cataract in mammals. |