abstract |
Described are polypeptides of factors stimulating the growth of human granulocyte-macrophage colonies (GM-CSF), as well as methods for structurally and antigenically synthesizing neutral muteins. The GM-CSFs described promote the growth and development of various hematopoietic lines, and may be useful in treatment conditions involving populations of weakened blood cells and / or regeneration of weakened blood cells, such as myeloid hypoplasia. , chronic infections, and hematopoiesis after bone marrow transplantation. The invention also includes a new mammalian expression vector. |