Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5c24684033fba97d1ad845ce453a57e3 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-06 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 |
filingDate |
1989-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1996-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_111b88ac4b20a00ba1110df78ed78de7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_754e9d48a4833e4eee52ae3f59544ac6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b6e3a5ce38882869e8583f6f90eecd9 |
publicationDate |
1996-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0367161-B1 |
titleOfInvention |
Process for selectively hydrolising fusion proteins |
abstract |
Polypeptides or proteins such as, for example, insulins or de-B<3><0>-insulins - especially human insulin or de-B<3><0>-human insulin - are prepared by enzymatic cleavage, using a trypsin-like endopeptidase, of specific fusion proteins which can be obtained by genetic manipulation and which contain the residue of a peptide-like alpha -amylase inhibitor in the molecule. The use of the specific fusion proteins results in a reaction product which can be worked up advantageously; the working-up can take place, where appropriate, by crystallisation. |
priorityDate |
1988-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |