| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5929f2d6f4dba84be8dd3a8ba633db12 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S930-26 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-57536 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-575
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 |
| filingDate |
1989-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c64739c6666d890132e045414cba1fa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53b830aead8feec25de9211e0ec6a708
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aace57a3162ba128e546159bf3464e8b |
| publicationDate |
1990-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0366016-A2 |
| titleOfInvention |
Endothelin DNA and use thereof |
| abstract |
Disclosed are (1) a DNA sequence containing a DNA segment coding for endothelin-2 or human endothelin-3, (2) a precursor protein and a mature peptide of endothelin-2 or human endothelin-3, (3) a transformant carrying a DNA sequence containing a DNA segment coding for endothelin-2 or human endothelin-3 and (4) a method for preparing mature endothelin-2 or endothelin-3 which comprises culturing the transformant described in (3), producing and accumulating a protein in a culture medium, and collecting the same. n Cells transfected or transformed with the DNA allow large amounts of endothelin-2 or endothelin-3 to be produced, which causes the advantageous production of endothelin-2 or endothelin-3. n Endothelin-2 and endothelin-3 can be utilized as hypotension therapeutic agents or local vasoconstrictors to animals including humans. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5492892-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009033761-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009033762-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9113089-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0315118-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0421284-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0484017-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0484017-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0315118-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5756344-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0468337-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6365725-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009033761-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009033762-A2 |
| priorityDate |
1988-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |