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filingDate 1989-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1994-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa30c0615be4166a198a94241ebc76ec
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3daccf5fcb716f482770532e9d64e901
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publicationDate 1994-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0364350-B1
titleOfInvention 4-Methyl-5[2-(4-phenyl-1-piperazinyl)-ethyl] thiazole derivatives, their preparation and pharmaceutical compositions containing them
abstract PCT No. PCT/FR89/00520 Sec. 371 Date Apr. 11, 1991 Sec. 102(e) Date Apr. 11, 1991 PCT Filed Oct. 10, 1989 PCT Pub. No. WO90/03972 PCT Pub. Date Apr. 19, 1990.The present invention relates to novel 4-methyl-5-[2-(4-phenylpiperazin-1-yl)ethyl]thiazole derivatives of the general formula <IMAGE> (I) in which R is selected from a hydrogen atom, an alkyl radical having from 2 to 7 carbon atoms and an aralkyl radical of which the aryl moiety preferably consists of phenyl and of which the alkyl moiety has from 1 to 4 carbon atoms, and to the pharmaceutically acceptable salts of these derivatives. It further relates to a method of preparing these products and to pharmaceutical compositions in which they are incorporated. These derivatives are applied especially in the preparation of drugs intended for the treatment of functional dysuria associated with hyperactivity of the alpha -adrenergic sympathetic nervous system.
priorityDate 1988-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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