http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0363869-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b09f893b262cefd50c5e76c4b85d1c0a |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-20 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-20 |
filingDate | 1989-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1994-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2fc59af9a9cfcc09a873cde921e6a2f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0206cca2d66592c6e224cd8d4075379b |
publicationDate | 1994-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0363869-B1 |
titleOfInvention | Substituted thienyl ethyl amines and process for their preparation |
abstract | Substituted thienylethylamines of the formula: <IMAGE> (IV) wherein R is formyl, acetyl or benzoyl or is benzyl, which is ring-substituted by at least one halogen atom, and R1 is a lower alkyl, phenyl or substituted phenyl, are initial products for the production of antithrombolytically effective pharmaceutical agents. A process for the production of the above-mentioned compounds from substituted ethanolamines by their reaction with strong bases, further reaction with the resultant aziridines with 2-thienyllithium, and conversion of the resultant thienylethylamines with compounds of formula RX, wherein R has the above-mentioned meaning and X is a halogen. |
priorityDate | 1988-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.