| abstract |
Aryl ureas and carbamic acid derivatives of formula nA-NHCW-Y-B nand pharmaceutically acceptable salts thereof nwherein A is a specified aromatic radical including 3,5-dichlorophenyl nW is O or S nY is NH or S nand B is a specified saturated azacyclic ring, eg tropan-3-yl or quinuclidin-3-yl, npossess 5-HT₃-antagonistic activity and are, for example, useful in treatment of migraine, emesis, anxiety, gastro-intestinal disorders and as anti-psychotics. |