Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b09f893b262cefd50c5e76c4b85d1c0a |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-04 |
filingDate |
1989-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2fc59af9a9cfcc09a873cde921e6a2f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16011061ca56d6887c21b84e348930ba |
publicationDate |
1990-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0360293-A2 |
titleOfInvention |
Process for the preparation of 4,5,6,7-tetrahydrothieno[3,2-c]pyridines |
abstract |
The invention relates to a new process for the preparation of 4,5,6,7-tetrahydro-thienopyridines of the formula n n n It is a 4-oxo-piperidine-3-carboxylic acid ester of the formula An allyl group is introduced in the 3 position, the ester function is removed in the 3 position, the resulting compound of the formula ozonized to the corresponding aldehyde of the formula reduced and ring-closed with H₂S / HCl in the presence of a metal halide to the end product.n n n These synthesized compounds have anti-thrombotic activity. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0573955-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5296603-A |
priorityDate |
1988-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |