http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0359593-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e2320c9c0a28a3bb46673630c38c746c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-755 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-755 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-18 |
| filingDate | 1989-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2004-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37156da56c498f5959d4d84a08805bb1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b934227bb529f781ae1e8690e8fffc98 |
| publicationDate | 2004-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0359593-B2 |
| titleOfInvention | Chromatographic separation of plasma proteins, particularly of factor VIII, of von Willebrand factor, of fibronectin and of fibrinogen |
| abstract | PCT No. PCT/FR89/00050 Sec. 371 Date Apr. 6, 1990 Sec. 102(e) Date Apr. 6, 1990 PCT Filed Feb. 8, 1989 PCT Pub. No. WO89/12065 PCT Pub. Date Dec. 14, 1989.The invention relates to a process for separating proteins from a fraction of human or animal plasma. According to this process, a solubilized fraction of cryoprecipitated plasma is subjected to a single stage of chromatography on a moderately ionic anion exchange resin permitting hydrophobic interactions to take place, which does not adsorb certain proteins and fixes others, which are then eluted by increasing the ionic strength of the buffer by the addition of NaCl. The process according to the invention makes it possible, in particular, to obtain a Factor VIII concentrate of high purity that can be used for the treatment of haemophilia A. The process also makes it possible to obtain concentrates of fibrinogen, Von Willebrand's factor and fibronectin. |
| priorityDate | 1988-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.