| abstract |
Compounds of the general formula (I)(R is H, alkyl, alkenyl, alkynyl, cycloalkyl, aralkyl or CHO, R' and R<sup>2</sup> are independently halogen, alkyl, alkoxy, hydroxyl, cyano, nitro or -NR<sup>3</sup>R<sup>4</sup> where R<sup>3</sup> and R<sup>4</sup> are independently H or alkyl and R<sup>2</sup> may be H) and their salts have selective α<sub>2</sub>- adrenoreceptor antagonist action.The compounds may be prepared by amination of compounds of the general formula (II)(where R<sup>1</sup> and R<sup>2</sup> are as defined above and X is a leaving group) |