http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0357638-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8381805eba6d034fc77bd230dd02e6e2 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-824 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-808 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-04 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-865 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 |
| filingDate | 1988-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4cd3eb0da77d7b4cb7025c0df1b5c9fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0eef06a755523811487971d4bca42d7 |
| publicationDate | 1990-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0357638-A1 |
| titleOfInvention | Regulation of amino acid synthesis using leu3 |
| abstract | LEU3, a leucine specific regulatory site, codes for a protein to regulate the RNA levels of a group of leucine specific genes. The protein encoded by LEU3 binds to a sequence of decanucleotide nuclei in the promoter regions of LEU1, LEU2, LEU4, ILV2 and, consequently, of ILV5. The largely conserved decanucleotide nucleus sequence shared by the binding sites of these genes is as follows: CCGGNNCCG G. Analysis of the DNA sequence of a LEU3 clone shows that it contains a reading structure open of 886 amino acids. A striking feature of the LEU3 protein is an agglomerate of acidic amino acids (19 of 20) which are located in half of the C-terminus of the coding region. The protein also has a repeated cysteine motif and a region of partial homology with MATalpha2 and the “homeo box” domain. LEU3, or part of LEU3 consisting of the 160 N-terminated amino acids and the 112 C-terminated amino acids, and the corresponding LEU3 decanucleotide linkage sequences are useful for the production or regulation of protein synthesis that does not include only the expression of LEU1, LEU2 and LEU4 but also any gene where the DNA binding sequences are incorporated into the 5 'region of the gene. |
| priorityDate | 1987-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 870.