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filingDate 1989-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1995-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8ee819f25a15af5c3db4e87b5783901
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publicationDate 1995-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0356335-B1
titleOfInvention Signal peptide and DNA sequences coding thereof
abstract The invention relates to a signal peptide of formula: MXKSTLLLLFLLLCLPSWNAGA where A = alanine C = cysteine F = phenylalanine G = glycine K = lysine L = leucine M = methionine N = asparagine P = proline S = serine T = threonine W = triptophane and X denotes a direct bond between M and K, an amino acid chosen from the group of the 20 amino acids of the genetic code or a peptide containing 2, 3 or 4 amino acids, each chosen independently of the others from the group of the 20 amino acids of the genetic code. It also relates to the DNA sequences coding for the latter, the expression vectors carrying one of these sequences, the Gram-negative bacteria transformed by these vectors and the process for periplasmic production of a polypeptide. Application: Manufacture of polypeptides such as hGH or hirudine.
priorityDate 1988-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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