abstract |
Novel acetamide compounds of the formula,n [wherein R₁ and R₂, each independently represents a hydrogen atom, a C₁ to C₆ straight- or branched-chain alkyl or alkenyl group, C₃ to C₆ cycloalkyl or cycloalkenyl group or an C₆ to C₁₀ aromatic group or R₁ and R₂ join with each other in combination with the adjacent N and carbon atoms or further with at least one of nitrogen, oxygen and sulfur atoms to represent a 5- or 6-membered heterocyclic ring group: R₃ represents a C₁-C₆ straight- or branched-chain alkyl or alkenyl group, C₃ to C₆ cycloalkyl or cycloalkenyl group, a halogen atom, a C₁-C₆ straight or branched-chain alkoxyl group, or a C₃-C₆ cycloalkoxy or cycloalkenoxy group and n is 0 to 4] and their pharmaceutically acceptable salts are useful in the treatment of ulcers in mammals. |