| abstract |
Compounds of formula I. in the R₁ is a lower alkyl or alkenyl group with 1-6 C atoms, a cycloalkyl radical with 3-7 C atoms, an aralkyl, aralkenyl or aryl radical, the respective aryl radical one or more times by halogen, C₁- C--alkyl , C₁-C₆-alkoxy, hydroxyl, trifluoromethyl, cyan, nitro, amino, C₁-C₆-alkylamino, C₂-C₁₂-dialkylamino, C₁-C₆-acylamino, C₁-C₁₆-acyl, C₁-C₆-alkylsulfenyl, -sulfinyl and -sulfonyl or substituted by azide, R₂ is a hydrogen atom, a C₁-C₆ alkyl, an aralkyl, an aralkenyl or an acyl group, A and B are a saturated or unsaturated alkylene chain with 1-10 carbon atoms, which can be substituted one or more times by C₁-C₃ alkyl groups, the sum of the carbon atoms of the chains A plus B being at least 4, but not more than 11, Q is oxygen, sulfur, a sulfonyl or sulfinyl group, or an amino group where the above definition applies to R₂, Y is a free carboxylic acid group, a carboxylic acid ester, a carboxylic acid amide or hydroxymethyl or tetrazolyl mean, their pharmacologically acceptable salts and optical and EZ isomers or their mixtures, processes for their preparation and medicaments containing these compounds for the treatment of metabolic disorders and / or circulatory disorders. |