http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0348641-A3
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D475-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D475-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D475-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-02 |
filingDate | 1989-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1991-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0348641-A3 |
titleOfInvention | Process for the preparation of tetrahydrofolates |
abstract | The invention relates to a new process for the preparation of 5,10-methenyl- (6R) -,n5-formyl- (6S) - and / or 5-methyl- (6S) -tetrahydrofolic acid and its salnzen, characterized in that one has an acid addition salt or the inner saltnof 5,10-methenyl- (6R, S) -tetrahydrofolic acid by diastereomer separationnsubjected to fractional crystallization and, if desired, the 5,10-Me obtainednthenyl- (6R) -tetrahydrofolic acid by treatment with a hydrolyzing agentnin 5-formyl- (6S) -tetrahydrofolic acid or by treatment with a reducing agentnAgent converted into 5-methyl- (6S) -tetrahydrofolic acid and / or a free one obtainednAcid converted into one of its salts by treatment with a base. |
priorityDate | 1988-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.