| abstract |
Described are novel quinolinecarboxylic acids of the general formulan wherein R¹ is C₁-C₄ alkyl, R² and R³ each is identically or differently hydrogen or C₁-C₄ alkyl, R⁴ is cyclopropyl, phenyl, halo-phenyl, or thienyl optionally substituted by C₁-C₄ alkyl or halogen, and R⁵ is halogen, nor pharmaceutically acceptable salts thereof having a more potent and longer lasting antibacterial activities against G(+) and G(-) bacteria than known analogues. |