| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c04a6880d1d21dfb790679b4749ed86f |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-3007 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 |
| filingDate |
1989-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_309e1e9cd19a5bf49a2f89ce117595e1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a226c8cee758e04d9bbcfdbe6220faf8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82cb258a1d5bdec73dadb0293445d2dc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e55f4a0eb90ecba50ecfeb442bb8376c |
| publicationDate |
1989-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0346702-A2 |
| titleOfInvention |
Transfectant cell lines which express isolated genes of the carcinoembryonic antigen family |
| abstract |
Non-human mammalian cell lines which express antigens of the carcinoembryonic antigen gene family are provided by the present invention. The cell lines are prepared by gene transfection of human DNA, such as LoVo cell DNA, into non-human mammalian cells, such as mouse cells or by the transfection of complete cDNA in appropriate expression vectors into non-human mammalian cells, such as mouse cells. Primary transfectants can be transfected further into non-human mammalian cells to provide secondary transfectants. Cloning of secondary transfectants yields cell lines that exhibit increased expression of the surface antigen protein. The transfectant cell lines provide a means for producing antibodies, particularly monoclonal antibodies, against CEA family antigens. Furthermore, a general method is provided for screening and assessing the specificity of these antibodies to each member of the CEA gene family. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5851764-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0641385-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6159751-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0549974-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0641385-A4 |
| priorityDate |
1988-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |