| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1374dd16777534b65ad4422333245af8 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-1133
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-811 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 |
| filingDate |
1988-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1994-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e5e739e875f91fd3ea48c6cb1e0435c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cdbeadd0798178afecfb3142b334cbad
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d0daf759845ca7b34cdffae313df0845
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_818000bee44d76d0163c01eca35b67b7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_568769f928bb6fbcafd3b227e231fc20 |
| publicationDate |
1994-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0346500-B1 |
| titleOfInvention |
Elastase inhibiting polypeptides and process for their preparation by genetic recombination |
| abstract |
Elastase inhibitors containing the amino-acid sequence (I) (i.e. the C-terminal portion of human polymorphonuclear leucocyte elastase inhibiting protein (SLPI)) are new: -(-ASN-PRO-THR-ARG-ARG- LYS-PRO-GLY-LYS- CYS-PRO-VAL-THR-TYR-GLY-GLN-CYS-LEU- MET-LEU-ASN-PRO-PRO- ASN-PHE-CYS-GLU-MET-ASP-GLY-GLN-CYS- LYS-ARG-ASP-LEU-LYS- CYS-CYS-MET-GLY-MET-CYS-GLY-LYS-SER- CYS-VAL-SER-PRO-VAL-LYS-ALA-)n- (I) (I) may have an N-terminal glycine, or the elastase inhibitor may have the formula Y-B-Z, where Y is a complete or partial human growth hormone sequence; B is a linking sequence; Z is (I). In (I), n is 1-10, and one or more of the cysteine residues may be in the sulphonic acid form. Pref. the human growth hormone sequence Y is PHE(1) to PHE(139) (esp. PHE(1) to GLN(122)). Pref. B are (ASN-GLY)n, (VAL-PRO-ARG)n or (LEU-VAL-PRO-ARG)n (where n is 1-10). Also claimed are DNA sequences coding for the elastase inhibitors, plasmids containing the DNA sequences, and transformant organisms containing the plasmids. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9108228-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9100912-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0164031-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9406454-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6869925-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5851983-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6017880-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-681350-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6132990-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5668107-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0616614-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5633227-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5871956-A |
| priorityDate |
1987-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |