| abstract |
Compounds are disclosed of formula (I) :n wherein nR₁ and R₂ are the same or different and are C₁₋₆ alkyl or C₃₋₆ alkenyl; or -NR₁R₂ forms a 5-membered (optionally containing an oxygen atom adjacent to the nitrogen) or a 6-membered ring, which ring optionally contains one unit of unsaturation and which is unsubstituted or substituted by hydroxy, oxo, optionally substituted methylidene, -COR₃ (where R₆ represents C₁₋₆ alkyl, OR₄ or -NHR₄, and R₄ represents hydrogen, C₁₋₆ alkyl, aryl, ar(C₁₋₆)alkyl) or =NOR₅ (where R₅ represents C₁₋₆ alkyl); nX represents a direct bond, -CH₂- or -CH₂O-; nAr represents a substituted phenyl moiety; nand physiologically acceptable salts thereof. n The compounds are indicated as useful for the treatment of pain and cerebral ischaemia. n Processes and intermediates for their preparation and pharmaceutical compositions containing them are also disclosed. |