| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-886 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-465 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00 |
| filingDate |
1989-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6cc80461b3311449ff3cfdbe5147d6d1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba365eb011074227e30fa40b57a1f413
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f16fcaf2b0c8ddc6688bd4636e06ce3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c087fd954b39622b9da3e6ef95a89c9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a06b2b1f6e05f18c607615be2f3b942 |
| publicationDate |
1989-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0346000-A2 |
| titleOfInvention |
Macrolide biosynthetic genes for use in streptomyces and other organisms |
| abstract |
Spiramycin antibiotic biosynthetic genes of Streptomyces ambofaciens are provided by the present invention, in addition to a variety of recombinant DNA vectors. The genes also function in other macrolide producing organisms. The genes can be used to increase or otherwise alter the macrolide antibiotic-producing ability of an organism. The present invention also provides host strains comprising mutant spiramycin biosynthetic genes which can be used to generate novel antibiotics. Also provided is a method for preparing the mutant gene comprising mutating cloned spiramycin biosynthetic DNA by transposon mutagenesis with subÂsequent transformation into a macrolide-antibiotic producing host and homologous recombination into its genome, to generate stable mutant cell lines. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5741675-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-651982-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7579167-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0468220-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0468217-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0468217-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5589385-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0791656-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1905833-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0791656-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0468220-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004033689-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004033689-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0524832-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0524832-A2 |
| priorityDate |
1988-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |