abstract |
Condensed diazepinones of the general formula I, <IMAGE> in which? B ○ represents one of the divalent radicals <IMAGE>, X¹ and X² represent the = CH group or, if? B ○ the radicals (S), (U) or (W ) means can also be nitrogen atoms, A is a C1 to C6 alkylene radical, R¹ and R² lower alkyl radicals or R¹ and R² together with the nitrogen atom also mean a saturated 4- to 7-membered heteroaliphatic ring, R³ is lower alkyl or hydrogen or chlorine, R <4> and R¹ ° are hydrogen or methyl, R <5> and R <6> are hydrogen, fluorine, chlorine, bromine or lower alkyl, R <7> are hydrogen, chlorine or methyl and R <8> and R <9> Hydrogen or lower alkyl, R 9 additionally denotes halogen, are suitable for the treatment of bradycardias and bradyarrhythmias. |