| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6cfc033f059d282fcd915bc8be2ae53f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-60 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0018
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6459
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21069 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 |
| filingDate |
1989-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ebf2a36c5dedbb6ba0e5c64d71fe3e1e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ccc5f2835f34c36a3d32b22ddee21dd8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ea825291be4fe2c4839cd3586261b4f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da007a9e00ea623df18d9e518a1242f6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efa534c59491067af98480920b488de0 |
| publicationDate |
1989-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0342931-A1 |
| titleOfInvention |
Method for the production of human tissue type plasminogen activator |
| abstract |
A method for the production of human tissue type plasminogen activator (tPA) using cells includes use of a p-aminomethyl benzoic acid derivative to supplement a cell culture medium or a tPA producing medium and further an increase of osmotic pressure in the medium to 350 milliosmoles or more per litre. The method can produce single-chain tPA in a high concentration and with a relatively small amount of double-chain tPA in the medium. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0756003-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0756003-A4 |
| priorityDate |
1988-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |