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filingDate 1989-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1990-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0342474-A3
titleOfInvention Use of diazepinones for the preparation of a medicament for therapy of microcirculatory disorders
abstract For diazepinones of the general formula I in the A is 5,11-dihydro-6H-pyrido [2,3-b] [1,4] benzodiazepin-6-one- bound in the 11-position, 5,10-dihydro-11H-dibenzo bound in the 5-position [b, e] [1,4] diazepin-11-one-, the 5-position bound 5,11-dihydro-10H-pyrido [3,2-b] [1,4] ben zodiazepin-10-one - Or the 4,9-di hydro-10H-thieno [3,4-b] [1,5] benzodiazepin-10-one group bound in the 4-position, which in the 1- and / or in the 3-position Alkyl radicals with 1 to 4 carbon atoms or in the 3-position can be substituted by chlorine, fluorine or bromine, the 6,11-dihydro-5H-pyrido [2,3-b] [1,5] benzodiazepine bound in the 11-position 5-one or the 4-bonded 1-methyl-1,4,9,10-tetrahydro pyrrolo [3,2-b] [1,5] benzodiazepin-10-one group, which is in the 3-position can be substituted by methyl or chlorine, R₁ represents a hydrogen atom or an alkyl group with 1 to 3 carbon atoms, R₂ is an alkyl group having 1 to 3 carbon atoms, and n and m, independently of one another, mean the integers 1 to 3, their isomers or enantiomers and their physiologically tolerable acid addition salts, if appropriate, have been found a new application as a means of treating disorders of the microcirculation, but in particular for treating shock conditions such as hemorrhagic shock .
priorityDate 1988-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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