http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0340780-A3
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H13-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H13-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H13-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-18 |
| filingDate | 1989-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1991-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0340780-A3 |
| titleOfInvention | Azidochlorination and diazidization of glycals |
| abstract | The invention describes a one-pot single step nprocedure for the azidochlorination or diazidization of nglycals, including glycal elements of carbohydrates. nCompounds such as 3,4,6-tri-O-benzyl-2-azido-2-deoxy-nalpha-D-galactopyranosyl chloride, and 3,4,6-tri-O-nbenzyl-2-azido-2-deoxy-alpha-,beta-D-galactopyranose nare prepared from tri-O-benzyl galactal as well as n3,4,6-tri-O-acetyl-2-azido-2-deoxy-D-alpha-ngalactopyranosyl chloride and 3,6,-di-O-acetyl-4-O-n[2,3,4,6-tetra-O-acetyl-beta-D-galactopyranosyl]-2-nazido-2-deoxy-alpha-D-glycopyranosyl chloride from ntheir respective O-acetylated glycal derivatives by the naddition of azido chloride which is chemically ngenerated in situ. A method using 3,4,6-tri-O-acetyl-n2-azido-2-deoxy-alpha-D-galacto-pyranosyl chloride for nthe synthesis of antigenic determinants such as the nterminal asialo GM₁(beta-D-Gal (1->3)-beta-D-GalNAc-OR) nhas been demonstrated. The conversion of the subject nsynthon into 3,4,6-tri-O-acetyl-2-azido-2-deoxy-alpha-nD-galactopyranosyl bromide and 1,3,4,6-tetra-O-acetyl-n2-azido-2-deoxy-alpha-D-galactopyranose is also ndescribed. A further method for the synthetic ngeneration of the Tn antigen (alpha-D-GalNAc-O-L-nserine) is also described. |
| priorityDate | 1988-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.