abstract |
Novel antibiotics TAN-1057 represented by the formula:n wherein, the absolute configuration in (A) is R or S, each R₁ and R₃ is a bonding hand or hydrogen, and R₂ is a bonding hand, provided that when R₂ binds with R₁ or R₃ the other is hydrogen, were produced by microorganisms belonging to the genus Flexibacter . TAN-1057 strongly inhibit the growth of pathogenic microorganisms and malignant tumors, thus being useful as therapeutic agents of infectious diseases or antitumor agents. |