| abstract |
PCT No. PCT/US87/03364 Sec. 371 Date Jun. 29, 1989 Sec. 102(e) Date Jun. 29, 1989 PCT Filed Dec. 22, 1987 PCT Pub. No. WO88/05045 PCT Pub. Date Jul. 14, 1988.This invention encompasses novel analogs of Leukotriene B4 which are selected from a compound of formula I, B-C APPROX C-CH2C(M2)-C APPROX C-Y-C(M1)-A, or formula II, B-C APPROX C-CH2C(M2)-C APPROX C-P-R5-A: wherein Y is: <IMAGE> <IMAGE> wherein P is: <IMAGE> <IMAGE> <IMAGE> Patentable intermediates, process for making the novel analogs and intermediates and preparation of useful pharmacological agents comprising the analogs and intermediates are part of this invention. |