http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0337627-A3
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-403 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-06 |
| filingDate | 1989-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1991-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0337627-A3 |
| titleOfInvention | 3-substituted-2-oxindole-1-carboxamides as inhibitors of interleukin-1 biosynthesis |
| abstract | This invention relates to the use of certain n3-substituted-2-oxindole-1-carboxamides of the formula n nand the pharmaceutically-acceptable base salts thereof nwherein X is H, Cl or F; Y is H or Cl; and R is benzyl nor thienyl to inhibit interleukin-1 biosynthesis in a nmammal. This invention also relates to the use of such ncompounds for treating interleukin-1 mediated disorders nand dysfunctions such as bone and connective tissue nmetabolism disorders and immune dysfunction in a nmammal. The methods of this invention comprise nadministering an interleukin-1 biosynthesis inhibiting namount of the compounds and salts of this invention to nsuch a mammal. |
| priorityDate | 1988-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.