| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e96496a9949403e2af2ca913e65bfec |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S930-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21007
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6435 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-68 |
| filingDate |
1988-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62da9bff7994e4f6ff4ddc6cd74b993b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd45a31a9709a80f6764ffd503e24904
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e41dc39340f1b60aad09b7705829ac97 |
| publicationDate |
1990-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0332678-A4 |
| titleOfInvention |
FIBRINOLYTIC PLASMINE OF MICROCOSPIC SIZE. |
| abstract |
Microplasmin and microplasminogen are plasmin and plasminogen derivatives produced by the action of plasmin non plasmin/plasminogen at high pH. The action of plasmin at this pH cleaves the heavy (A) chain of plasmin at the Arg529-Lys503 or Lys530-Leu531 bond and promotes disulfide bond rearrangement, producing microplasmin or microplasminogen consisting of a 30 or 31 residue C-terminal peptide derived from the A chain bound through new disulfide bonds to the intact B-chain of plasmin or plasminogen. The resulting products are significantly reduced in size and retain native activity. |
| priorityDate |
1987-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |