abstract |
Secondary formamides having the structural formula: nR¹CHR²CH(OR³)NHCHO nwherein: nR¹ is H, C₁-C₆ alkyl or aryl; nR² is H, or C₁-C₆ alkyl; and nR³ is benzyl, C₁-C₈ alkyl or hydroxyalkyl; nare synthesized by reacting an acetal having the structural formula: R¹CHR²CH(OR³)₂ wherein R¹, R² and R³ are as defined above, with formamide in the presence of a strong acid catalyst at a temperature in the range of 0°-200°C. |