| abstract |
The new compounds of the general formula wherein R1 and R2 are independently lower alkyl; or together represent alkylene with 3-5 C atoms in a straight chain; one of R³ and R⁴ is hydrogen and the other is hydrogen or lower alkyl; R⁶ and R⁷ are hydrogen or lower alkyl; R⁵ and R⁸ are hydrogen, lower alkyl, lower alkoxy or halogen; X -O-, -S-, -SO-, -SO₂- or -NR⁹; R⁹ is hydrogen, lower alkyl or acyl; Y is -S (O) m R¹⁰ or -NHet, and, if X is -NR⁹-, -S-, -SO- or -SO₂-, is also -N (R¹¹) ₂ or -OR¹²; R¹⁰ lower alkyl; R¹¹ and R¹² are hydrogen, lower alkyl or acyl; -NHet a 5-8-membered, saturated or unsaturated monocyclic heterocycle bonded via an N atom; n is 2, 3 or 4 and m is 0, 1 or 2. can be used as active ingredients for the treatment of diseases, for example neoplasias, dermatoses or aging skin. |