| abstract |
Methods and compositions for HIV-1 diagnosis, treatment, and vaccination include one or more peptides which correspond to antigenic determinants encoded by conserved regions of the HIV-1 genome. The peptides will be immunologically cross-reactive with such antigenic determinant sites and, preferably, will be capable of eliciting a serum-neutralizing response when administered to an individual who may or may not be infected with HIV-1. Antibodies to such peptides will also find use in the present invention. |