abstract |
A method for producing an α-aspartylphenylalanine derivative nrepresented by formula (II) comprises reacting a nβ-aspartylphenylalanine derivative represented by formula (I) n nwherein R₁ and R₂ represent hydrogen or an alkyl group having 1 nto 4 carbon atoms, with a basic compound in a solvent in the npresence of an inorganic compound or an organic compound of nzinc, copper, nickel, magnesium, aluminum, iron, tin, silicon nand/or titanium. |