http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0326364-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7f6e33603375c486b0ab3505830af9e8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0207 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0227 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-02 |
| filingDate | 1989-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1994-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec29adb9d81ec59d7fc26f6b9dd02d29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08aaeaf45620ef9ca8c8bfc0f3512d9f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0f6f5f3e8baaef43640e66188d46e06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9bbab51a62e215c35f7f336753c22e7d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ad61e6c362ab93e4369fc67982474d1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fadc226c4c59f509af42960242ea3264 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_714c0f9d52a8c8ab92a34ccc22e6c452 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_337b16d3b626dedacbacde74bc979aa6 |
| publicationDate | 1994-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0326364-B1 |
| titleOfInvention | Renin inhibitory oligopeptides, their preparation and use |
| abstract | Compounds of formula (I): <CHEM> [in which: A is a carbon-carbon bond or C1 - C3 alkylene; B is imino group or C1 - C2 alkylene; R<1> is C1 - C4 alkyl, C1 - C4 alkoxy, heterocyclic or optionally substituted amino; R<2> is optionally substituted phenyl or optionally substituted naphthyl; R<3> is thiazolyl, isoxazolyl or imidazolyl; R<4> is isopropyl or cyclohexyl; R<5> and R<6> are C1 - C4 alkyl, or, together with the carbon atom to which they are attached, C3 - C7 cycloalkyl; R<7> is hydrogen or optionally substituted C1 - C6 alkyl; and R<8> is hydrogen or C1 - C4 alkyl] have renin-inhibitory and, hence, hypotensive activities and are of value in the diagnosis and treatment of hypertension induced by failures in the renin-angiotensin system. They may be prepared by reacting together appropriate amino acids, lower oligopeptides or derivatives thereof. |
| priorityDate | 1988-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 511.