Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_945325b0bd69fa2f6c53369051ab92e7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c1e92522145228b7deebede508907153 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2458-40 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-533 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-536 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-533 |
filingDate |
1987-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ccb9240a72dc71c30f7845d66fbce3fe |
publicationDate |
1989-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0324759-A1 |
titleOfInvention |
METHOD FOR DETERMINING A BIOLOGICAL SUBSTANCE COMPRISING A MARKING USING A METAL CHELATE. |
abstract |
A biological substance is determined using a label comprising a lanthanide or other metal ion coupled to the biological substance using a chelate-forming compound. The chelated complex thus formed is dissociated by reducing the ambient pH to a level low enough to release the metal ion, which is then subjected to chelation with a separate chelating chromophore, accompanied by an increase in pH to a value. close to the optimum for determining the metal chelation chromophore by fluorescence spectroscopy, luminometry, colorimetry or other similar techniques. |
priorityDate |
1986-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |