abstract |
1,4-dihydropyridine derivatives represented by the formula:n wherein nR¹ and R², different from the other, is selected from the group consisting of lower alkyl, lower alkenyl, lower alkoxyalkyl or aminoaryl(lower)alkyl having carbon atoms of 1 to 6, which may be substituted or unsubstituted by a lower alkyl having carbon atoms of 1 to 4, wherein at least one of R¹ and R² is a lower alkenyl having carbon atoms of 3 to 6 whose 1- or 2- position is substituted by a lower alkyl having carbon atoms of 1 to 4; and nR³ is a nitro group in ortho-, meta- or para-position of the phenyl. n The compounds are useful as vasodilators and in the treatment of hypertension. |