| abstract |
Imidazole derivatives of the general formula I wherein R¹ is hydrogen, an optionally substituted C₁₋₁₀ hydrocarbon or hetaryl radical or a cyclic ether radical, R² is hydrogen, halogen, an optionally substituted amino, nitro, azide, thiocyanate or cyano group, an optionally halogen-substituted straight or branched C₁₋₁₀ alkyl radical or -OR¹ with R¹ in the abovementioned meaning and R¹ and R² together with the oxygen atom form a saturated or unsaturated 5- to 7-membered ring which can also contain another heteroatom, R³ is hydrogen, a straight or branched C₁₋₆-alkyl group or a C₁₋₆-alkoxyalkyl group, R⁴ -COOR⁵, -CONR⁶R⁷, -CN with R⁵ in the meaning of hydrogen, a straight or branched C₁₋₆-alkyl group, R⁶ and R⁷ are the same or different and represent hydrogen or a straight, branched or cyclic alkyl group having up to 7 carbon atoms or together with the nitrogen atom form an optionally a further heteroatom-containing five or six-membered ring, R⁸ in the meaning of hydrogen or a straight, branched or cyclic alkyl group with up to 7 carbon atoms, where R² may be one or more times on the phenyl radical are described, as well as the process for their preparation and their use as medicaments. |