Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_151f1bc34a6ad88c064ab834688e8f7f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f7a4ac64b3b5d019d543ccf200e75dd7 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D281-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-56 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D281-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-26 |
filingDate |
1987-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c38128f40395f600263cb6a6c43d4c0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e25c439451531b3717921279f198040 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8699bec7cd192b70f5f4f59b26268bb4 |
publicationDate |
1989-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0320532-A1 |
titleOfInvention |
Novel optically active carboxylic acid derivative l-lysine salt and process for production thereof |
abstract |
A novel salt of d-threo-2-hydroxy-3-(2-amino-phenylthio)-3-(4-methoxyphenyl)-propionic acid represented by the following formula (1)n wherein C* represents the carbon atoms of the optically resolved molecules,n with L-lysine. The above compound can be produced by reacting d1-threo-2-hydroxy-3-(2-aminophenylthio)-3-(4-methoxyphenyl)-propionic acid with L-lysine or a metal salt of said propionic acid with an acid salt of L-lysine to form corresponding salts, and separating the difficultly-soluble salt from the resulting two optically active salts by utilizing the difference in solubility in a solvent between the two optically active salts. This compound is useful as a synthesis intermediate for a known pharmaceutical compound, diltiazem hydrochloride. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9100270-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2650272-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BE-1003314-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2033575-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AT-400143-B |
priorityDate |
1986-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |