http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0318392-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-6561 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6561 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-547 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-675 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-475 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-40 |
| filingDate | 1988-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1992-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1992-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0318392-B1 |
| titleOfInvention | N-(vinblastinoyl-23)derivatives of 1-amino methylphosphonic acids, processes for their preparation and pharmaceutical compositions containing them |
| abstract | N-(23-Vinblastinoyl) derivatives of 1-aminomethylphosphonic acid, of general formula I: n<IMAGE>n n<??>In which:n - R1 denotes a hydrogen atom, a linear or branched alkyl radical containing from 1 to 6 carbon atoms, a linear or branched alkylene radical containing from 1 to 6 carbon atoms, an arylalkyl radical of 7 to 10 carbon atoms capable of carrying as substituent on the aromatic ring a halogen atom, a hydroxyl radical or an alkyl or alkoxy radical, each containing from 1 to 5 carbon atoms, a 2-indolylmethyl radical, a 4-imidazolylmethyl radical, or an alkoxycarbonylmethyl radical containing from 3 to 11 carbon atoms,n - each of R2 and R3, which are identical or different, denotes a linear or branched alkyl radical containing from 1 to 4 carbon atoms,n in the form of mixture of diastereo isomers or of pure isomers, their Nb'-oxides and their addition salts with a pharmaceutically acceptable inorganic or organic acid. n<??>These compounds are antitumoral agents. |
| priorityDate | 1987-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 65.