| abstract |
Platelet Activating Factor (PAF) antagonists which ncomprises the compounds of the formula (I): n nwherein A is an optionally substituted phenyl or an noptionally substituted heterocyclic group; X is methylene ngroup, carbonyl group or thiocarbonyl group; R¹, R² and R³ nare independently a lower alkyl group, and their salts are nexcellent in absorption from the intestinal canal. n Among the compounds of the formula (I), those wherein nA is an optionally substituted 2,3-dihydro-1-benzoxepin-4-nyl group are novel compounds and exhibit excellent PAF nantagonism. |