http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0309624-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b55c349b43c3ecba4977fd52cc8f8c67 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0014 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-22 |
| filingDate | 1987-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9af578cdd0369cfdb13d02aaf59673c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9836527cbb5f52d2be1bf932ea93b54a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1bf442149f001955056b96ebb97f52d |
| publicationDate | 1989-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0309624-A1 |
| titleOfInvention | Composition for enhancing percutaneous administration of medicine |
| abstract | A composition for enhancing percutaneous absorption of a pharmaceutical substance contains a proline ester (I) or prolinol ester (II) <CHEM> wherein R1 and R3 are hydrogen or aliphatic hydrocarbon residue, R2 and R4 are aliphatic hydrocarbon residues, the carbon atoms not exceeding 20 in R1 and R2 and 18 in R3 and R4, and the ring N-atom can be quaternised to form a salt with an acid; synthesis of these compounds is described. Usually a polar liquid is included e.g. an alcohol, glycerin or an ester thereof, a thioglycerol, lactic ester, ethyleneurea amide, glycol, lactone, pyrrolidone or lactam compound, in amount of 30-99.5 wt% of the ester and polar compound. The active ingredient can be applied separately to the skin or preferably incorporated in the composition, to provide topical or systemic effects. Numerous types of ingredients can be used. The composition can be incorporated in an ointment, lotion, gel, plaster or tape. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0374218-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9845233-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9845233-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0374218-A4 |
| priorityDate | 1986-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 703.