http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0309300-A2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8286bde48d5077479faf28ad8a98b003 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07G13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-22 |
filingDate | 1988-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7207537383e9fcf204136ccd3c11bbe4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c30de3dbbf9c575f314945fabfe86dd1 |
publicationDate | 1989-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0309300-A2 |
titleOfInvention | Process for the preparation of dimethylglycylgluconic-acid salts |
abstract | The present invention relates to a new process for the synthesis of pangamic acid salts (sometimes also designated by vitamin B₁₅ and more precisely called dimethylglycyl-gluconates). This process consists of the esterification of gluconic acid or calcium or magnesium gluconate with dimethylglycine hydrochloride in an aqueous medium in the presence of phosphoric acid or sulfuric acid at a temperature varying between 30 ° and 70 ° C. ; then in the concentration of the esterification product, followed by the elimination of mineral acids by the action of a high molecular weight amine insoluble in water. The pangamic acid obtained is then transformed into one of its salts by the action of a carbonate, such as for example calcium carbonate or magnesium carbonate.n n n Pangamates are useful in medicine to combat various forms of arteriosclerosis. |
priorityDate | 1987-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 68.