| abstract |
Bispidine derivatives of the formula I <IMAGE> in which R, R¹ and R³ are identical or different and are H, C1-C4-alkyl, halogen or C1-C4-alkoxy, and R² when Y = -? - is C1-C4-alkyl , Halogen, -CN, C1-C4-alkoxy, -NHSO2CH3, -CF3, NH-acetyl and -NR <4> R <5>, where R <4> and R <5> represent C1-C4-alkyl, and when Y = -? -NH-, C1-C4-alkyl, halogen, -CN, C1-C4-alkoxy, -NHSO2CH3, -CF3, NH-acetyl and -NR <9> R¹ °, where R < 9> C1-C4-alkyl and R¹ ° H or C1-C4-alkyl, and R², if X = CH2, can also be NO2 and NH2, X is -CH2-, -C (O) - or -C (R <6>) OR <7> - (in which R <6> denotes H, C1-C4-alkyl and R <7> H, C1-C4-alkyl and <IMAGE>, with R <8> in the meaning of H, C1-C4-alkyl, halogen or C1-C4-alkoxy), Y -C (O) - or -CONH- and Z mean C1-C4-alkylene, which can be olefinically unsaturated and / or branched, and their physiologically tolerable salts. |