Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0786796fc7c819ceda6f75a7022596b2 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2123-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-1045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-30 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-10 |
filingDate |
1988-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_674dad7a58bb55677663acb2dbeccf87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c94d702c9bc0133f95e4946914720fe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_680a72ea2c5d4bc6f22ec7259dd385f1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c29c2460d3223da2dbc28db96a67b96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_47cdfcce9b4bf2b9fe80576245b15a2f |
publicationDate |
1989-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0308265-A2 |
titleOfInvention |
Methods and compositions relating to regression-associated antigens |
abstract |
Regression associated antigens (RAAs) are identified in material from neoplastic cells by their immunological reactivity with regression associated antibodies from the serum of patients diagnosed as undergoing regression of a tumor. Regression associated antibodies (RAAbs) are identified by their absence during progression of a neoplastic disease state and by their presence in a diagnosed state of regression. The antigens are purified, used to monitor the condition of cancer patients, and production of antibodies and treatments employing those antibodies are described. It is also disclosed that RAAs are expressed by M . hyorhinis and may be expressed by expression of provided nucleotide sequences in recombinant host cells. RAAs and nucleic acids encoding RAAs (or portions thereof) and RAAbs may be used in diagnostic assays and immunotherapy. RAAbs and fragments portion thereof may be used in passive immunization therapy and radioisotope or magnetic resonance scanning. A monoclonal RAAb and a hybrdoma secreting it are also provided. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016090383-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10996222-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0578356-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5874546-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108070560-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0578356-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0510691-A1 |
priorityDate |
1987-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |